High quality Calcium Hydroxyapatite Powder with good Price
High quality Calcium Hydroxyapatite Powder with Best Price
Hydroxyapatite, also called hydroxylapatite (HA), is a naturally occurring mineral form of calcium apatite with the formula Ca5(PO4)3(OH), but is usually written Ca10(PO4)6(OH)2 to denote that the crystal unit cell comprises two entities. Hydroxylapatite is the hydroxyl endmember of the complex apatite group. The OH− ion can be replaced by fluoride, chloride or carbonate, producing fluorapatite or chlorapatite. It crystallizes in the hexagonal crystal system. Pure hydroxylapatite powder is white. Naturally occurring apatites can, however, also have brown, yellow, or green colorations, comparable to the discolorations of dental fluorosis.
High quality Calcium Hydroxyapatite Powder with Best Price
Hydroxylapatite is commonly used as a filler to replace amputated bone or as a coating to promote bone ingrowth into prosthetic implants. Although many other phases exist with similar or even identical chemical makeup, the body responds to them very differently. Coral skeletons can be transformed into hydroxylapatite by high temperatures; their porous structure allows relatively rapid ingrowth at the expense of initial mechanical strength. The high temperature also burns away any organic molecules such as proteins, preventing an immune response and rejection.
Many modern implants, e.g. hip replacements, dental implants and bone conduction implants, are coated with hydroxylapatite. It has been suggested that this may promote osseointegration.[citation needed] Porous hydroxylapatite implants are used for local drug delivery in bone. It is also being used to repair early lesions in tooth enamel.
In spite of attractive biological properties, hydroxylapatite, and materials based thereon, have some drawbacks, such as low bioresorption rate in vivo, poor stimulating effect on the growth of new bone tissues, low crack resistance and small fatigue durability in the physiological environment. The application of modified hydroxylapatite opens up the opportunities for the preparation of artificial bone substances for implants and a large variety of drugs for curing different lesions of bone, soft and mucous tissues of the individual. A promising method of modification is the introduction of fluorine or silicon into the primary structure with the formation of fluorine- or silicon-substituted hydroxylapatite. The introduction of fluorine increases the resistance to biodegradation[18] and improves the adsorption of proteins and adhesion of the coating to the metal substrate.
Microcrystalline hydroxylapatite (MH) is marketed as a "bone-building" supplement with superior absorption in comparison to calcium. It is a second-generation calcium supplement derived from bovine bone. In the 1980s, bone meal calcium supplements were found to be contaminated with heavy metals, and although the manufacturers claim their MH is free from contaminants, people are advised to avoid it because its effect in the body has not been well-tested. However, the limited tests seem to show positive results. A 1995 randomized placebo-controlled study of 40 people in Europe found that it was more effective than calcium carbonate in slowing bone loss. A 2007 randomized double-blind controlled study of an MH supplement called the Bone Builder found significant positive effects in bone mineral density (BMD) compared to control.[21] Hydroxylapatite has been used by Noel Fitzpatrick to facilitate bionic development in animals, by coating steel rods in hydroxylapatite to encourage natural growth of skin around it. As a component of nanocomposites, hydroxylapatite is finding uses as a potential new bone replacement materials.
High quality Calcium Hydroxyapatite Powder with Best Price
1. Main Used For Toothpaste for Following benefits:
Health Whitening , Remove plaque, Improve gum problems, Prevent tooth decay and Fresh breath.
2. Applications For Pharmaceutical Field:
A. Bone replacement materials, plastic and cosmetic surgery, dental, chromatography purification, calcium supplement, is currently widely used in manufacturing with the tip of the teeth or bones composition new stuff.
B. Hydroxyapatite widely exists in the human body and milk, are mainly distributed in the human body in the bones and teeth, mainly distributed in the casein micelle in milk and whey.
3. Healthy Supplement:
Microcrystalline hydroxylapatite (MH) is marketed as a "bone-building" supplement with superior absorption in comparison to calcium.
